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Cellosaurus Ishikawa 1-E-8 (CVCL_W424)

[Text version]
Cell line name Ishikawa 1-E-8
Accession CVCL_W424
Resource Identification Initiative To cite this cell line use: Ishikawa 1-E-8 (RRID:CVCL_W424)
Comments Population: Japanese.
Doubling time: 38.9 hours (PubMed=9183638).
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2529 (Ishikawa)
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line
Publications

PubMed=9183638
Nishida M., Kasahara K., Oki A., Satoh T., Arai Y., Kubo T.
Establishment of eighteen clones of Ishikawa cells.
Hum. Cell 9:109-116(1996)

DOI=10.1007/978-4-431-53981-0_2
Nishida M.
Ishikawa cells: opening of in vitro hormone research on endometrial carcinoma.
(In) Cell and molecular biology of endometrial carcinoma; Kuramoto H., Nishida M. (eds.); pp.35-58; Springer; Tokyo (2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W424
Encyclopedic resources Wikidata; Q54898287
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number10