ID   PX24
AC   CVCL_W374
DR   cancercelllines; CVCL_W374
DR   Wikidata; Q54948746
RX   PubMed=21166887;
CC   Problematic cell line: Contaminated. Parent cell line (OV-2008) has been shown to be a ME-180 derivative.
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
CC   Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
DI   NCIt; C27676; Human papillomavirus-related cervical squamous cell carcinoma
DI   ORDO; Orphanet_213767; Squamous cell carcinoma of the cervix uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0473 ! OV-2008
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 05-10-23; Version: 16
RX   PubMed=21166887; DOI=10.1111/j.1749-0774.2010.00098.x;
RA   Nakajima K., Isonishi S., Saito M., Tachibana T., Ishikawa H.;
RT   "Characterization of two independent, exposure-time dependent
RT   paclitaxel-resistant human ovarian carcinoma cell lines.";
RL   Hum. Cell 23:156-163(2010).