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Cellosaurus SPC-A1/DTX (CVCL_W217)

[Text version]
Cell line name SPC-A1/DTX
Synonyms SPC-A1/docetaxel
Accession CVCL_W217
Resource Identification Initiative To cite this cell line use: SPC-A1/DTX (RRID:CVCL_W217)
Comments Problematic cell line: Contaminated. Parent cell line (SPC-A1) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI:4672; Docetaxel anhydrous (Taxotere).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6955 (SPC-A1)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=22460125; DOI=10.2119/molmed.2011.00230
Wang R., Huang J.-Y., Feng B., De W., Chen L.-B.
Identification of ING4 (inhibitor of growth 4) as a modulator of docetaxel sensitivity in human lung adenocarcinoma.
Mol. Med. 18:874-886(2012)

PubMed=23035364; DOI=10.3727/096504012X13425470196218
Song H.-Z., Yi J., Chen J., Chen L.-B.
Nimotuzumab increases chemosensitivity of human lung adenocarcinoma cell lines to docetaxel.
Oncol. Res. 20:39-47(2012)

Encyclopedic resources Wikidata; Q54955523
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number9