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Cellosaurus A549/TXL10 (CVCL_W190)

[Text version]
Cell line name A549/TXL10
Accession CVCL_W190
Resource Identification Initiative To cite this cell line use: A549/TXL10 (RRID:CVCL_W190)
Comments Population: Caucasian.
Doubling time: 75.5 hours (CelloPub=CLPUB00006).
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

CLPUB00006
Wang Z.-J., Li M., Zhao W.-C., Zhao G.-Q., Dong Z.-M.
Establishment and characterization of lung adenocarcinoma cell lines with multidrug resistance.
Life Sci. J. 4:13-16(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W190
Encyclopedic resources Wikidata; Q54607052
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number15