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Cellosaurus O24B (CVCL_W083)

[Text version]
Cell line name O24B
Accession CVCL_W083
Resource Identification Initiative To cite this cell line use: O24B (RRID:CVCL_W083)
Comments Omics: SNP array analysis.
Sequence variations
  • Mutation; HGNC; HGNC:950; BAP1; Simple; p.Gln322fs*9 (c.966_978del13); Zygosity=Homozygous (PubMed=21642991).
Disease Pleural malignant mesothelioma (NCIt: C7376)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W083
Biological sample resources BioSamples; SAMEA100789
Encyclopedic resources Wikidata; Q54931663
Gene expression databases GEO; GSM726280
Polymorphism and mutation databases Cosmic; 1522767
Progenetix; CVCL_W083
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number13