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Cellosaurus MUG-Mel1 (CVCL_VV72)

[Text version]
Cell line name MUG-Mel1
Synonyms MUG Mel1; MUGMel1; Medical University of Graz-Melanoma 1
Accession CVCL_VV72
Resource Identification Initiative To cite this cell line use: MUG-Mel1 (RRID:CVCL_VV72)
Comments Doubling time: 32.16 +- 4.28 hours (PubMed=30858407).
Omics: SNP array analysis.
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Lys1745Glu (c.5233A>G); Zygosity=Heterozygous (PubMed=30858407).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VV73 (MUG-Mel1 clone C8)CVCL_VV74 (MUG-Mel1 clone D5)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): PubMed=30858407

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135817,18
D5S81812
D7S8208,11
D8S117913,14
D13S31711,12
D16S53911
D18S5113,14
D21S1131,31.2
FGA21,24
Penta D9,10
Penta E5,12
TH019.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=29069749; DOI=10.18632/oncotarget.17823; PMCID=PMC5641092
Riedl S., Rinner B., Schaider H., Liegl-Atzwanger B., Meditz K., Preishuber-Pflugl J., Grissenberger S., Lohner K., Zweytick D.
In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumor peptide R-DIM-P-LF11-334 on human malignant melanoma.
Oncotarget 8:71817-71832(2017)

PubMed=30858407; DOI=10.1038/s41598-019-40570-1; PMCID=PMC6411871
Heitzer E., Groenewoud A., Meditz K., Lohberger B., Liegl-Atzwanger B., Prokesch A., Kashofer K., Behrens D., Haybaeck J., Kolb-Lenz D., Koefeler H., Riedl S., Schaider H., Fischer C., Snaar-Jagalska B.E., de Jong D., Szuhai K., Zweytick D., Rinner B.
Human melanoma brain metastases cell line MUG-Mel1, isolated clones and their detailed characterization.
Sci. Rep. 9:4096-4096(2019)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL4630709
ChEMBL-Targets; CHEMBL4630715
PubChem_Cell_line; CVCL_VV72
Encyclopedic resources Wikidata; Q95991469
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number8