ID   ICC5
AC   CVCL_VV28
DR   cancercelllines; CVCL_VV28
DR   Cell_Model_Passport; SIDM01803
DR   DepMap; ACH-001845
DR   Wikidata; Q94313317
RX   PubMed=27231123;
RX   PubMed=35640676;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: 5 days (Direct_author_submission).
CC   Sequence variation: Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Val (c.394_395CG>GT); Zygosity=Unspecified (PubMed=27231123; DepMap=ACH-001845).
CC   Miscellaneous: Doubling time and age/sex of donor from personal communication of El-Bardeesy, Nabeel.
ST   Source(s): DepMap=ACH-001845
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 9,14
ST   D16S539: 13
ST   D18S51: 15,17
ST   D21S11: 28,32.2
ST   D3S1358: 14
ST   D5S818: 12,13
ST   D7S820: 10
ST   D8S1179: 14
ST   FGA: 23,25
ST   Penta D: 10,11
ST   Penta E: 9,11
ST   TH01: 9,10
ST   TPOX: 8
ST   vWA: 21
DI   NCIt; C35417; Intrahepatic cholangiocarcinoma
DI   ORDO; Orphanet_70567; Cholangiocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   73Y
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 10-09-24; Version: 11
//
RX   PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737;
RA   Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C.,
RA   Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K.,
RA   Greninger P., McDermott U., Garnett M.J., Jenkins R.L.,
RA   Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y.,
RA   Goyal L., Ferrone C.R., Zhu A.X.-X., Joung J.K., Shokat K.M., Benes C.H.,
RA   El-Bardeesy N.;
RT   "Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity
RT   and SRC dependence in intrahepatic cholangiocarcinoma.";
RL   Cancer Discov. 6:727-739(2016).
//
RX   PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155;
RA   Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y.,
RA   Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S.,
RA   Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.;
RT   "Development and characterization of human primary cholangiocarcinoma
RT   cell lines.";
RL   Am. J. Pathol. 192:1200-1217(2022).
//