ID   KUL84-MEL
AC   CVCL_VU99
DR   cancercelllines; CVCL_VU99
DR   Wikidata; Q95980473
RX   PubMed=20099279;
RX   PubMed=22850568;
CC   From: Ludwig Institute for Cancer Research, Brussels Branch; Brussels; Belgium.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=22850568).
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 19-12-24; Version: 7
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RX   PubMed=20099279; DOI=10.1002/ijc.25182;
RA   Kholmanskikh O., van Baren N., Brasseur F., Ottaviani S., Vanacker J.,
RA   Arts N., van der Bruggen P., Coulie P.G., De Plaen E.;
RT   "Interleukins 1alpha and 1beta secreted by some melanoma cell lines
RT   strongly reduce expression of MITF-M and melanocyte differentiation
RT   antigens.";
RL   Int. J. Cancer 127:1625-1636(2010).
//
RX   PubMed=22850568; DOI=10.1158/1078-0432.CCR-12-1632; PMCID=PMC3463754;
RA   Khalili J.S., Liu S.-J., Rodriguez-Cruz T.G., Whittington M., Wardell S.,
RA   Liu C.-W., Zhang M.-Y., Cooper Z.A., Frederick D.T., Li Y.-F., Zhang M.,
RA   Joseph R.W., Bernatchez C., Ekmekcioglu S., Grimm E.A., Radvanyi L.G.,
RA   Davis R.E., Davies M.A., Wargo J.A., Hwu P., Lizee G.A.;
RT   "Oncogenic BRAF(V600E) promotes stromal cell-mediated
RT   immunosuppression via induction of interleukin-1 in melanoma.";
RL   Clin. Cancer Res. 18:5329-5340(2012).
//