ID   SCCOHT-1
AC   CVCL_VU69
SY   SCCOHT1; Small Cell Carcinoma of the Ovary, Hypercalcemic Type-1
DR   BTO; BTO:0005853
DR   cancercelllines; CVCL_VU69
DR   Cell_Model_Passport; SIDM01866
DR   DepMap; ACH-001279
DR   GEO; GSM1622408
DR   GEO; GSM2748144
DR   GEO; GSM2748145
DR   GEO; GSM2748146
DR   GEO; GSM2748147
DR   GEO; GSM2748148
DR   GEO; GSM2748149
DR   Millipore; SCC437
DR   Wikidata; Q98129384
RX   PubMed=22581215;
RX   PubMed=26356327;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: 38.1 hours (PubMed=22581215).
CC   Sequence variation: Mutation; HGNC; 11100; SMARCA4; Simple; p.Arg1077Ter (c.3229C>T); ClinVar=VCV001692588; Zygosity=Heterozygous (DepMap=ACH-001279).
CC   Omics: Array-based CGH.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
DI   NCIt; C40439; Ovarian small cell carcinoma, hypercalcemic type
DI   ORDO; Orphanet_370396; Small cell carcinoma of the ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   31Y
CA   Cancer cell line
DT   Created: 24-05-19; Last updated: 02-05-24; Version: 12
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RX   PubMed=22581215; DOI=10.3892/ijo.2012.1468;
RA   Otte A., Gohring G., Steinemann D., Schlegelberger B., Groos S.,
RA   Langer F., Kreipe H.-H., Schambach A., Neumann T., Hillemanns P.,
RA   Park-Simon T.-W., Hass R.;
RT   "A tumor-derived population (SCCOHT-1) as cellular model for a small
RT   cell ovarian carcinoma of the hypercalcemic type.";
RL   Int. J. Oncol. 41:765-775(2012).
//
RX   PubMed=26356327; DOI=10.1002/path.4633;
RA   Karnezis A.N., Wang Y.-M., Ramos P., Hendricks W.P.D., Oliva E.,
RA   D'Angelo E., Prat J., Nucci M.R., Nielsen T.O., Chow C., Leung S.,
RA   Kommoss F., Kommoss S., Silva A., Ronnett B.M., Rabban J.T. III,
RA   Bowtell D.D.L., Weissman B.E., Trent J.M., Gilks C.B., Huntsman D.G.;
RT   "Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM
RT   is highly sensitive and specific for small cell carcinoma of the
RT   ovary, hypercalcaemic type.";
RL   J. Pathol. 238:389-400(2016).
//