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Cellosaurus R7080-6 (CVCL_VU48)

[Text version]
Cell line name R7080-6
Accession CVCL_VU48
Resource Identification Initiative To cite this cell line use: R7080-6 (RRID:CVCL_VU48)
Comments Doubling time: 16-20 hours (PubMed=8668197).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:12833; XRCC5.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4055; XRCC6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS:0000215.
Hierarchy Parent: CVCL_VU46 (R70-15)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=8668197; DOI=10.1128/mcb.16.7.3799; PMCID=PMC231376
Yang S.-H., Nussenzweig A., Li L.-G., Kim D., Ouyang H.-H., Burgman P., Li G.C.
Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits.
Mol. Cell. Biol. 16:3799-3806(1996)

PubMed=9724713; DOI=10.1073/pnas.95.18.10390; PMCID=PMC27904
Ghoshal K., Li Z.-L., Jacob S.T.
Overexpression of the large subunit of the protein Ku suppresses metallothionein-I induction by heavy metals.
Proc. Natl. Acad. Sci. U.S.A. 95:10390-10395(1998)

Cross-references
Encyclopedic resources Wikidata; Q98128786
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number8