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Cellosaurus CHO-K1 MMC-2 (CVCL_VU06)

[Text version]
Cell line name CHO-K1 MMC-2
Synonyms MMC-2; CHO-MMC-2
Accession CVCL_VU06
Resource Identification Initiative To cite this cell line use: CHO-K1 MMC-2 (RRID:CVCL_VU06)
Comments Characteristics: Sensitive to mitomycin C.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; A0MQ57; Ercc3; Simple; p.Gln739Ter (c.2215C>T); Zygosity=Unspecified (PubMed=16143348).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=2413991
Robson C.N., Harris A.L., Hickson I.D.
Isolation and characterization of Chinese hamster ovary cell lines sensitive to mitomycin C and bleomycin.
Cancer Res. 45:5304-5309(1985)

PubMed=3093856; DOI=10.1016/0027-5107(86)90049-7
Robson C.N., Hickson I.D.
Genetic analysis of mitomycin-C-sensitive mutants of a Chinese hamster ovary cell line.
Mutat. Res. 163:201-208(1986)

PubMed=2110815; DOI=10.1038/bjc.1990.162; PMCID=PMC1971598
Keohane A., Godden J., Stratford I.J., Adams G.E.
The effects of three bioreductive drugs (mitomycin C, RSU-1069 and SR4233) on cell lines selected for their sensitivity to mitomycin C or ionising radiation.
Br. J. Cancer 61:722-726(1990)

PubMed=16143348; DOI=10.1016/j.mrfmmm.2005.07.013
Hall H., Gursky J., Nicodemou A., Rybanska I., Kimlickova E., Pirsel M.
Characterization of ERCC3 mutations in the Chinese hamster ovary 27-1, UV24 and MMC-2 cell lines.
Mutat. Res. 593:177-186(2006)

Cross-references
Encyclopedic resources Wikidata; Q93451806
Entry history
Entry creation24-May-2019
Last entry update30-Jan-2024
Version number7