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Cellosaurus KTRC SIX2:EGFP (CVCL_VU01)

[Text version]
Cell line name KTRC SIX2:EGFP
Synonyms 2429iPS SIX2:EGFP; Kidney Translational Research Center SIX2:EGFP iPSC
Accession CVCL_VU01
Resource Identification Initiative To cite this cell line use: KTRC SIX2:EGFP (RRID:CVCL_VU01)
Comments Population: Caucasian.
Characteristics: Identifies mesenchymal nephron progenitors (NPs), early nephron populations (PubMed=31492807).
Characteristics: Using CRISPR/Cas9 SIX2 has been endogenously tagged at the C-terminal of both alleles with EGFP (PubMed=31492807).
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2769 (CCD-1112Sk)
Children:
CVCL_E5VQ (KTRC SIX2:EGFP/CITED1:mCherry)
Sex of cell Male
Age at sampling <1M
Category Induced pluripotent stem cell
Web pages Provider; KTRC; -; https://www.atlas-d2k.org/chaise/record/#2/Cell_Line:Reporter_Cell_Line/RID=14-3QDM
Publications

PubMed=31492807; DOI=10.1681/ASN.2019030303; PMCID=PMC6779359
Vanslambrouck J.M., Wilson S.B., Tan K.S., Soo J.Y.-C., Scurr M., Spijker H.S., Starks L.T., Neilson A., Cui X.-X., Jain S., Little M.H., Howden S.E.
A toolbox to characterize human induced pluripotent stem cell-derived kidney cell types and organoids.
J. Am. Soc. Nephrol. 30:1811-1823(2019)

Cross-references
Encyclopedic resources Wikidata; Q93302352
Entry history
Entry creation24-May-2019
Last entry update10-Apr-2025
Version number9