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Cellosaurus HEL69.5 (CVCL_VT45)

[Text version]
Cell line name HEL69.5
Accession CVCL_VT45
Resource Identification Initiative To cite this cell line use: HEL69.5 (RRID:CVCL_VT45)
Comments From: University of Helsinki; Helsinki; Finland.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Sequence variations
Disease Fragile X syndrome (NCIt: C84717)
Fragile X syndrome (ORDO: Orphanet_908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Children
Category Induced pluripotent stem cell
Publications

PubMed=27411166; DOI=10.1002/dneu.22419
Achuta V.S., Grym H., Putkonen N., Louhivuori V., Karkkainen V., Koistinaho J., Roybon L., Castren M.L.
Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome.
Dev. Neurobiol. 77:438-453(2017)

PubMed=29339535; DOI=10.1126/scisignal.aan8784
Achuta V.S., Moykkynen T., Peteri U.-K., Turconi G., Rivera C., Keinanen K.P., Castren M.L.
Functional changes of AMPA responses in human induced pluripotent stem cell-derived neural progenitors in fragile X syndrome.
Sci. Signal. 11:eaan8784.1-eaan8784.11(2018)

PubMed=30503263; DOI=10.1016/j.stemcr.2018.11.003; PMCID=PMC6294261
Danesi C., Achuta V.S., Corcoran P., Peteri U.-K., Turconi G., Matsui N., Albayrak I., Rezov V., Isaksson A., Castren M.L.
Increased calcium influx through L-type calcium channels in human and mouse neural progenitors lacking fragile X mental retardation protein.
Stem Cell Reports 11:1449-1461(2018)

Cross-references
Encyclopedic resources Wikidata; Q94096141
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number10