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Cellosaurus QIMR-WK1 (CVCL_VS54)

[Text version]
Cell line name QIMR-WK1
Synonyms WK1; QIMR-B012
Accession CVCL_VS54
Resource Identification Initiative To cite this cell line use: QIMR-WK1 (RRID:CVCL_VS54)
Comments Doubling time: 46.2 +- 1.0 hours (PubMed=30894629).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain, right parieto-occipital lobe.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (QCell).
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (QCell).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Tyr (c.3139C>T); ClinVar=VCV000039705; Zygosity=Heterozygous (QCell).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 77Y
Category Cancer cell line
STR profile Source(s): PubMed=30894629

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,13
D7S8208,11
D13S31712,13
D16S53911,12
D21S1127,28
TH016,9.3
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pages https://www.qimrberghofer.edu.au/our-research/commercialisation/q-cell/
Publications

PubMed=30894629; DOI=10.1038/s41598-019-41277-z; PMCID=PMC6427001
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 9:4902-4902(2019)

PubMed=31965010; DOI=10.1038/s41598-020-57850-w; PMCID=PMC6972897
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
Publisher correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 10:1185-1185(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VS54
Encyclopedic resources Wikidata; Q98128771
Gene expression databases GEO; GSM3347680
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number10