ID   QIMR-SB2b
AC   CVCL_VS52
SY   SB2b; QIMR-B010
DR   cancercelllines; CVCL_VS52
DR   GEO; GSM3347678
DR   Wikidata; Q98128769
RX   PubMed=30894629;
RX   PubMed=31965010;
WW   https://www.qimrberghofer.edu.au/commercial-collaborations/partner-with-us/q-cell/
CC   Doubling time: 108.7 +- 6.9 hours (PubMed=30894629).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (QCell).
CC   Sequence variation: Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Heterozygous (QCell).
CC   Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Ala289Val (c.866C>T); ClinVar=VCV000376209; Zygosity=Heterozygous (QCell).
CC   Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.His304Tyr (c.910C>T); Zygosity=Heterozygous (QCell).
CC   Sequence variation: Mutation; HGNC; HGNC:6973; MDM2; Simple; p.Trp329Cys (c.987G>T); Zygosity=Heterozygous (QCell).
CC   Sequence variation: Mutation; HGNC; HGNC:7029; MET; Simple; p.Cys800Phe (c.2399G>T) (p.Cys818Phe, c.2453G>T); ClinVar=VCV000648391; Zygosity=Heterozygous (QCell).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Tyr1021His (c.3061T>C); ClinVar=VCV001691391; Zygosity=Heterozygous (QCell).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Brain, right parietal lobe; UBERON=UBERON_0002803.
ST   Source(s): PubMed=30894629
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 12
ST   D16S539: 9,12
ST   D21S11: 28,32
ST   D5S818: 11,13
ST   D7S820: 11,12
ST   TH01: 6,7
ST   TPOX: 9,10
ST   vWA: 17
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   48Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 19-12-24; Version: 11
//
RX   PubMed=30894629; DOI=10.1038/s41598-019-41277-z; PMCID=PMC6427001;
RA   Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S.,
RA   Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S.,
RA   Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D.,
RA   Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.;
RT   "A reference collection of patient-derived cell line and xenograft
RT   models of proneural, classical and mesenchymal glioblastoma.";
RL   Sci. Rep. 9:4902-4902(2019).
//
RX   PubMed=31965010; DOI=10.1038/s41598-020-57850-w; PMCID=PMC6972897;
RA   Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S.,
RA   Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S.,
RA   Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D.,
RA   Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.;
RT   "Publisher correction: A reference collection of patient-derived cell
RT   line and xenograft models of proneural, classical and mesenchymal
RT   glioblastoma.";
RL   Sci. Rep. 10:1185-1185(2020).
//