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Cellosaurus QIMR-MMK1 (CVCL_VS47)

[Text version]
Cell line name QIMR-MMK1
Synonyms MMK1; QIMR-B005
Accession CVCL_VS47
Resource Identification Initiative To cite this cell line use: QIMR-MMK1 (RRID:CVCL_VS47)
Comments Doubling time: 52.4 +- 4.5 hours (PubMed=30894629).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain, right temporal lobe; UBERON=UBERON_0002809.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Heterozygous (QCell).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Tyr183Cys (c.548A>G); ClinVar=VCV000134517; Zygosity=Heterozygous (QCell).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Phe56Val (c.166T>G); ClinVar=VCV000924880; Zygosity=Homozygous (QCell).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 80Y
Category Cancer cell line
STR profile Source(s): PubMed=30894629

Markers:
AmelogeninX
CSF1PO10,11
D5S81812
D7S8209,10
D13S31713
D16S53911,13
D21S1127,33.2
TH016,10
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Web pages https://www.qimrberghofer.edu.au/commercial-collaborations/partner-with-us/q-cell/
Publications

PubMed=30894629; DOI=10.1038/s41598-019-41277-z; PMCID=PMC6427001
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 9:4902-4902(2019)

PubMed=31965010; DOI=10.1038/s41598-020-57850-w; PMCID=PMC6972897
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
Publisher correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 10:1185-1185(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VS47
Encyclopedic resources Wikidata; Q98128764
Gene expression databases GEO; GSM3347673
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number10