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Cellosaurus QIMR-JK2 (CVCL_VS46)

[Text version]
Cell line name QIMR-JK2
Synonyms JK2; QIMR-B004
Accession CVCL_VS46
Resource Identification Initiative To cite this cell line use: QIMR-JK2 (RRID:CVCL_VS46)
Comments Doubling time: 94.2 +- 6.0 hours (PubMed=30894629).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain, right frontal lobe; UBERON=UBERON_0002810.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (QCell).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Leu (c.329G>T); ClinVar=VCV000406597; Zygosity=Homozygous (QCell).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): PubMed=30894629

Markers:
AmelogeninX,Y
CSF1PO12
D5S81810,11
D7S8208
D13S3178,11
D16S53912
D21S1128
TH017,9
TPOX8,11
vWA15,20

Run an STR similarity search on this cell line
Web pages https://www.qimrberghofer.edu.au/commercial-collaborations/partner-with-us/q-cell/
Publications

PubMed=30894629; DOI=10.1038/s41598-019-41277-z; PMCID=PMC6427001
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 9:4902-4902(2019)

PubMed=31965010; DOI=10.1038/s41598-020-57850-w; PMCID=PMC6972897
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
Publisher correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 10:1185-1185(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VS46
Encyclopedic resources Wikidata; Q98128763
Gene expression databases GEO; GSM3347672
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number10