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Cellosaurus QIMR-HW1 (CVCL_VS45)

[Text version]
Cell line name QIMR-HW1
Synonyms HW1; QIMR-B003
Accession CVCL_VS45
Resource Identification Initiative To cite this cell line use: QIMR-HW1 (RRID:CVCL_VS45)
Comments Doubling time: 55.8 +- 2.7 hours (PubMed=30894629).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain, right fronto-parietal lobe.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (QCell).
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Ala289Val (c.866C>T); ClinVar=VCV000376209; Zygosity=Heterozygous (QCell).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): PubMed=30894629

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S8208,10
D13S31712
D16S53913
D21S1128,29
TH016,9
TPOX8
vWA15,18

Run an STR similarity search on this cell line
Web pages https://www.qimrberghofer.edu.au/commercial-collaborations/partner-with-us/q-cell/
Publications

PubMed=30894629; DOI=10.1038/s41598-019-41277-z; PMCID=PMC6427001
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 9:4902-4902(2019)

PubMed=31965010; DOI=10.1038/s41598-020-57850-w; PMCID=PMC6972897
Stringer B.W., Day B.W., D'Souza R.C.J., Jamieson P.R., Ensbey K.S., Bruce Z.C., Lim Y.-C., Goasdoue K., Offenhauser C., Akgul S., Allan S., Robertson T., Lucas P.G., Tollesson G., Campbell S., Winter C., Do H.-D., Dobrovic A., Inglis P.-L., Jeffree R.L., Johns T.G., Boyd A.W.
Publisher correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 10:1185-1185(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VS45
Encyclopedic resources Wikidata; Q98128762
Gene expression databases GEO; GSM3347671
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number10