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Cellosaurus Hermes 2B (CVCL_VS08)

[Text version]
Cell line name Hermes 2B
Synonyms Hermes 2b; Hermes2B; Human extended-replication melanocytes-2B
Accession CVCL_VS08
Resource Identification Initiative To cite this cell line use: Hermes 2B (RRID:CVCL_VS08)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Melanocyte of skin; CL=CL_1000458.
Sequence variations
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VS15 (Hmel-p16-2)
Sex of cell Female
Age at sampling 28Y
Category Telomerase immortalized cell line
Publications

PubMed=12759390; DOI=10.1093/jnci/95.10.723
Sviderskaya E.V., Gray-Schopfer V.C., Hill S.P., Smit N.P., Evans-Whipp T.J., Bond J., Hill L., Bataille V., Peters G., Kipling D., Wynford-Thomas D., Bennett D.C.
p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression.
J. Natl. Cancer Inst. 95:723-732(2003)

PubMed=21343389; DOI=10.1158/0008-5472.CAN-10-2958; PMCID=PMC3070783
Rose A.E., Poliseno L., Wang J.-H., Clark M., Pearlman A., Wang G.-M., Vega y Saenz de Miera E.C., Medicherla R., Christos P.J., Shapiro R., Pavlick A., Darvishian F., Zavadil J., Polsky D., Hernando E., Ostrer H., Osman I.
Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.
Cancer Res. 71:2561-2571(2011)

Cross-references
Encyclopedic resources Wikidata; Q94104106
Gene expression databases GEO; GSM555118
GEO; GSM555170
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number11