ID   LL-iPSC-AECII
AC   CVCL_VR37
SY   (LL)-iPSC-AECII; Long-Lasting-iPSC derived Alveolar Epithelial Cells type II
DR   Wikidata; Q95982405
RX   PubMed=30211653;
CC   Population: Caucasian.
CC   Characteristics: This cell line was established in a three step process: 1) iPSCs were generated from the parent fibroblast cell line; 2) these iPSCs were differentiated into alveolar type II epithelial cells (AEC type II); 3) these AEC type II cells were immortalized by transduction with human BMI1 and TERT (PubMed=30211653).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1066; BMI1.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Alveolar type 2 fibroblast; CL=CL_4028006.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2769 ! CCD-1112Sk
SX   Male
AG   <1M
CA   Telomerase immortalized cell line
DT   Created: 13-11-18; Last updated: 19-12-24; Version: 10
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RX   PubMed=30211653; DOI=10.1152/ajplung.00357.2017;
RA   Tamo L., Hibaoui Y., Kallol S., Alves M.P., Albrecht C.,
RA   Hostettler K.E., Feki A., Rougier J.-S., Abriel H., Knudsen L.,
RA   Gazdhar A., Geiser T.;
RT   "Generation of an alveolar epithelial type II cell line from induced
RT   pluripotent stem cells.";
RL   Am. J. Physiol. Lung Cell. Mol. Physiol. 315:L921-L932(2018).
//