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Cellosaurus MCF7-h14 (CVCL_VR08)

[Text version]
Cell line name MCF7-h14
Accession CVCL_VR08
Resource Identification Initiative To cite this cell line use: MCF7-h14 (RRID:CVCL_VR08)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4421; GNRHR.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

CLPUB00443
Meyer C.
Characterisation of the direct antiproliferative effects of a gonadotrophin-releasing hormone analogue.
Thesis PhD (2012); University of Edinburgh; Edinburgh; United Kingdom

Cross-references
Cell line databases/resources cancercelllines; CVCL_VR08
Encyclopedic resources Wikidata; Q95986791
Entry history
Entry creation13-Nov-2018
Last entry update19-Dec-2024
Version number11