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Cellosaurus Panc-1-CTC (CVCL_VQ69)

[Text version]
Cell line name Panc-1-CTC
Synonyms Panc-1-Circulating Tumor Cells
Accession CVCL_VQ69
Resource Identification Initiative To cite this cell line use: Panc-1-CTC (RRID:CVCL_VQ69)
Comments Population: Caucasian.
Characteristics: Exhibits more profound migratory and invasive abilities than the parent cell line in vitro. Has a higher tumor-forming ability than the parent cell line in vivo.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=30156359; DOI=10.1111/cas.13783; PMCID=PMC6215881
Sato T., Muramatsu T., Tanabe M., Inazawa J.
Identification and characterization of transforming growth factor beta induced in circulating tumor cell subline from pancreatic cancer cell line.
Cancer Sci. 109:3623-3633(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VQ69
Encyclopedic resources Wikidata; Q98128480
Gene expression databases GEO; GSM3333106
GEO; GSM3333107
GEO; GSM3333110
GEO; GSM3333111
Entry history
Entry creation13-Nov-2018
Last entry update05-Oct-2023
Version number9