• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=29492214).
  
• Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Trp110Ter (c.330G>A) (p.Gly125Arg, c.373G>A); ClinVar=VCV000376303; Zygosity=Unspecified (PubMed=29492214).
  

PubMed=10837406; DOI=10.1093/intimm/12.6.787
Pirozzi G., Lombari V., Zanzi D., Ionna F., Lombardi M.L., Errico S., Ruggiero G., Manzo C.
CD40 expressed on human melanoma cells mediates T cell co-stimulation and tumor cell growth.
Int. Immunol. 12:787-795(2000)

PubMed=12488552; DOI=10.1124/mol.63.1.192
Tentori L., Portarena I., Barbarino M., Balduzzi A., Levati L., Vergati M., Biroccio A., Gold B., Lombardi M.L., Graziani G.
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.
Mol. Pharmacol. 63:192-202(2003)

PubMed=16638848; DOI=10.1158/1078-0432.CCR-05-1940
Scala S., Giuliano P., Ascierto P.A., Ierano C., Franco R., Napolitano M., Ottaiano A., Lombardi M.L., Luongo M., Simeone E., Castiglia D., Mauro F., De Michele I., Calemma R., Botti G., Caraco C., Nicoletti G., Satriano R.A., Castello G.
Human melanoma metastases express functional CXCR4.
Clin. Cancer Res. 12:2427-2433(2006)

PubMed=21424129; DOI=10.3892/or.2011.1220
Manca A., Sini M.C., Izzo F., Ascierto P.A., Tatangelo F., Botti G., Gentilcore G., Capone M., Mozzillo N., Rozzo C., Cossu A., Tanda F., Palmieri G.
Induction of arginosuccinate synthetase (ASS) expression affects the antiproliferative activity of arginine deiminase (ADI) in melanoma cells.
Oncol. Rep. 25:1495-1502(2011)

PubMed=21863025; DOI=10.1038/bjc.2011.324; PMCID=PMC3185940
De Luca A., Lamura L., Strizzi L., Roma C., D'Antonio A., Margaryan N.V., Pirozzi G., Hsu M.-Y., Botti G., Mari E., Hendrix M.J.C., Salomon D.S., Normanno N.
Expression and functional role of CRIPTO-1 in cutaneous melanoma.
Br. J. Cancer 105:1030-1038(2011)

PubMed=29492214; DOI=10.18632/oncotarget.23989; PMCID=PMC5823576
Sini M.C., Doneddu V., Paliogiannis P., Casula M., Colombino M., Manca A., Botti G., Ascierto P.A., Lissia A., Cossu A., Palmieri G.
Genetic alterations in main candidate genes during melanoma progression.
Oncotarget 9:8531-8541(2018)