ID   CFBE41o- 4.7 DeltaF508-CFTR
AC   CVCL_VP35
SY   CFBE41oc4-4.7deltaF
DR   Millipore; SCC159
DR   Wikidata; Q93447380
RX   PubMed=18769032;
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Unspecified; Note=In the 2 genomic alleles while the transfected copies are p.Phe508del (c.1522-1524delTTT) (PubMed=18769032).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1884; CFTR (Note=With p.Phe508del (c.1522_1524delTTT)).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
ST   Source(s): Millipore=SCC159
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 9,11
ST   D16S539: 12
ST   D18S51: 15,16
ST   D21S11: 29,31.2
ST   D3S1358: 16,18
ST   D5S818: 11,13
ST   D7S820: 8,11
ST   D8S1179: 11,14
ST   FGA: 22,24
ST   Penta D: 12
ST   Penta E: 12
ST   TH01: 9.3
ST   TPOX: 8,9
ST   vWA: 17
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_HL93 ! CFBE41o-
SX   Sex unspecified
AG   Age unspecified
CA   Transformed cell line
DT   Created: 07-09-18; Last updated: 19-12-24; Version: 16
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RX   PubMed=18769032; DOI=10.1159/000149783; PMCID=PMC2927120;
RA   Illek B., Maurisse R., Wahler L., Kunzelmann K., Fischer H.,
RA   Gruenert D.C.;
RT   "Cl transport in complemented CF bronchial epithelial cells correlates
RT   with CFTR mRNA expression levels.";
RL   Cell. Physiol. Biochem. 22:57-68(2008).
//