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Cellosaurus SVG-A Msh3 1.7X (CVCL_VP19)

[Text version]
Cell line name SVG-A Msh3 1.7X
Accession CVCL_VP19
Resource Identification Initiative To cite this cell line use: SVG-A Msh3 1.7X (RRID:CVCL_VP19)
Comments Characteristics: Compared to wild-type SVG-A, has a 1.7 times expression level of MSH3.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7326; MSH3.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7326; MSH3.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238.
Cell type: Astrocyte; CL=CL_0000127.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VP18 (SVG-A Msh3-/-)
Sex of cell Male
Age at sampling 8-12FW
Category Transformed cell line
Publications

PubMed=28973443; DOI=10.1093/nar/gkx650; PMCID=PMC5622409
Keogh N., Chan K.Y., Li G.-M., Lahue R.S.
MutSbeta abundance and Msh3 ATP hydrolysis activity are important drivers of CTG*CAG repeat expansions.
Nucleic Acids Res. 45:10068-10078(2017)

Cross-references
Cell line collections (Providers) CancerTools; 153691
Ximbio; 153691
Encyclopedic resources Wikidata; Q98132898
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number9