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Cellosaurus CUTC60 (CVCL_VM61)

[Text version]
Cell line name CUTC60
Accession CVCL_VM61
Resource Identification Initiative To cite this cell line use: CUTC60 (RRID:CVCL_VM61)
Comments Doubling time: 22 hours (PubMed=30733375).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): PubMed=30733375; PubMed=30737244

Markers:
AmelogeninX
CSF1PO10,12
D3S135817,18
D5S81810,12
D7S8208
D8S117914,16
D13S3179
D16S5399,10
D18S5115
D21S1132.2
FGA20
TH016,8
TPOX8,11
vWA16,18

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Publications

PubMed=30733375; DOI=10.1158/1541-7786.MCR-18-1026; PMCID=PMC6711777
Schweppe R.E., Pozdeyev N., Pike L.A., Korch C.T., Zhou Q., Sams S.B., Sharma V., Pugazhenthi U., Raeburn C.D., Albuja-Cruz M.B., Reigan P., LaBarbera D.V., Landa-Lopez I., Knauf J.A., Fagin J.A., Haugen B.R.
Establishment and characterization of four novel thyroid cancer cell lines and PDX models expressing the RET/PTC1 rearrangement, BRAFV600E, or RASQ61R as drivers.
Mol. Cancer Res. 17:1036-1048(2019)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953; PMCID=PMC6522280
Landa I., Pozdeyev N., Korch C.T., Marlow L.A., Smallridge R.C., Copland J.A. 3rd, Henderson Y.C., Lai S.Y., Clayman G.L., Onoda N., Tan A.-C., Garcia-Rendueles M.E.R., Knauf J.A., Haugen B.R., Fagin J.A., Schweppe R.E.
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VM61
Encyclopedic resources Wikidata; Q93460551
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number12