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Cellosaurus WTC11 HOPX-NLS-eGFP (CVCL_VM46)

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Cell line name WTC11 HOPX-NLS-eGFP
Accession CVCL_VM46
Resource Identification Initiative To cite this cell line use: WTC11 HOPX-NLS-eGFP (RRID:CVCL_VM46)
Comments Population: Japanese.
Characteristics: Using TALEN, a conditionally expressed HOPX-NLS-eGFP construct was introduced in the AAVS1 safe harbor locus (PubMed=30290179).
Genetic integration: Method=TALEN; Gene=HGNC; HGNC:24961; HOPX.
Genetic integration: Method=TALEN; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y803 (GM25256)
Sex of cell Male
Age at sampling 30Y
Category Induced pluripotent stem cell
Publications

PubMed=30290179; DOI=10.1016/j.stem.2018.09.009; PMCID=PMC6220122
Friedman C.E., Nguyen Q., Lukowski S.W., Helfer A., Chiu H.S., Miklas J., Levy S., Suo S.-B., Han J.-D.J., Osteil P., Peng G.-D., Jing N.-H., Baillie G.J., Senabouth A., Christ A.N., Bruxner T.J.C., Murry C.E., Wong E.S., Ding J., Wang Y.-L., Hudson J., Ruohola-Baker H., Bar-Joseph Z., Tam P.P.L., Powell J.E., Palpant N.J.
Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation.
Cell Stem Cell 23:586-598.e8(2018)

Cross-references
Encyclopedic resources Wikidata; Q98135094
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number9