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Cellosaurus RUES2 HOPX-tdTomato (CVCL_VM29)

[Text version]
Cell line name RUES2 HOPX-tdTomato
Synonyms RUES2 HOPX-td-Tomato
Accession CVCL_VM29
Resource Identification Initiative To cite this cell line use: RUES2 HOPX-tdTomato (RRID:CVCL_VM29)
Comments Characteristics: Using CRISPR/Cas9 a tdTomato-pA-loxP-PGKp-PuroR-pA-loxP was integrated at the HOPX translational start site.
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; PGG5S; tdTomato (Note=Bright red fluorescent protein derived from drFP583 (DsRed)).
Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B810 (RUES2)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=28813672; DOI=10.1016/j.celrep.2017.07.067; PMCID=PMC5576510
Palpant N.J., Wang Y.-L., Hadland B., Zaunbrecher R.J., Redd M., Jones D., Pabon L., Jain R., Epstein J., Ruzzo W.L., Zheng Y., Bernstein I.D., Margolin A.A., Murry C.E.
Chromatin and transcriptional analysis of mesoderm progenitor cells Identifies HOPX as a regulator of primitive hematopoiesis.
Cell Rep. 20:1597-1608(2017)

Cross-references
Encyclopedic resources Wikidata; Q98129218
Entry history
Entry creation07-Sep-2018
Last entry update10-Sep-2024
Version number9