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Cellosaurus RUES2 HOPX KO (CVCL_VM28)

[Text version]
Cell line name RUES2 HOPX KO
Accession CVCL_VM28
Resource Identification Initiative To cite this cell line use: RUES2 HOPX KO (RRID:CVCL_VM28)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:24961; HOPX.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B810 (RUES2)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=28813672; DOI=10.1016/j.celrep.2017.07.067; PMCID=PMC5576510
Palpant N.J., Wang Y.-L., Hadland B., Zaunbrecher R.J., Redd M., Jones D., Pabon L., Jain R., Epstein J., Ruzzo W.L., Zheng Y., Bernstein I.D., Margolin A.A., Murry C.E.
Chromatin and transcriptional analysis of mesoderm progenitor cells Identifies HOPX as a regulator of primitive hematopoiesis.
Cell Rep. 20:1597-1608(2017)

PubMed=30290179; DOI=10.1016/j.stem.2018.09.009; PMCID=PMC6220122
Friedman C.E., Nguyen Q., Lukowski S.W., Helfer A., Chiu H.S., Miklas J., Levy S., Suo S.-B., Han J.-D.J., Osteil P., Peng G.-D., Jing N.-H., Baillie G.J., Senabouth A., Christ A.N., Bruxner T.J.C., Murry C.E., Wong E.S., Ding J., Wang Y.-L., Hudson J., Ruohola-Baker H., Bar-Joseph Z., Tam P.P.L., Powell J.E., Palpant N.J.
Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation.
Cell Stem Cell 23:586-598.e8(2018)

Cross-references
Encyclopedic resources Wikidata; Q98129217
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number5