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Cellosaurus Oli-neuM (CVCL_VL76)

[Text version]
Cell line name Oli-neuM
Accession CVCL_VL76
Resource Identification Initiative To cite this cell line use: Oli-neuM (RRID:CVCL_VL76)
Comments Characteristics: Expression of MRF/Myrf promotes the differentiation of this cell line up to the premyelination stage without the addition of chemical compounds (PubMed=26658258).
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:2684944; Myrf.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: Activated EGFR-neu.
Derived from site: In situ; Embryonic brain; UBERON=UBERON_0006238.
Cell type: Oligodendrocyte; CL=CL_0000128.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NMRI.
Hierarchy Parent: CVCL_IZ82 (Oli-neu)
Sex of cell Sex unspecified
Age at sampling 15FD
Category Transformed cell line
Publications

PubMed=26658258; DOI=10.1371/journal.pone.0144550; PMCID=PMC4689554
Porcu G., Serone E., De Nardis V., Di Giandomenico D., Lucisano G., Scardapane M., Poma A., Ragnini-Wilson A.
Clobetasol and halcinonide act as Smoothened agonists to promote myelin gene expression and RxRgamma receptor activation.
PLoS ONE 10:E0144550-E0144550(2015)

Cross-references
Encyclopedic resources Wikidata; Q98128338
Entry history
Entry creation07-Sep-2018
Last entry update10-Sep-2024
Version number6