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Cellosaurus JPO9 (CVCL_VL73)

[Text version]
Cell line name JPO9
Synonyms CHO-JPO9; CHO/JPO9; JP09
Accession CVCL_VL73
Resource Identification Initiative To cite this cell line use: JPO9 (RRID:CVCL_VL73)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:12373; TSHR.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=2171505; DOI=10.1016/0006-291X(90)90789-P
Perret J., Ludgate M., Libert F., Gerard C., Dumont J.-E., Vassart G., Parmentier M.
Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones.
Biochem. Biophys. Res. Commun. 171:1044-1050(1990)

PubMed=7836899; DOI=10.1677/joe.0.1430527
MacNeil S., Munro D.S., Metcalfe R.A., Cotterell S., Ruban L.N., Davies R., Weetman A.P.
An investigation of the ability of TSH and Graves' immunoglobulin G to increase intracellular calcium in human thyroid cells, rat FRTL-5 thyroid cells and eukaryotic cells transfected with the human TSH receptor.
J. Endocrinol. 143:527-540(1994)

PubMed=7912172; DOI=10.1111/j.1365-2265.1994.tb03017.x
Michelangeli V.P., Munro D.S., Poon C.W., Frauman A.G., Colman P.G.
Measurement of thyroid stimulating immunoglobulins in a new cell line transfected with a functional human TSH receptor (JPO9 cells), compared with an assay using FRTL-5 cells.
Clin. Endocrinol. (Oxf.) 40:645-652(1994)

PubMed=9691974; DOI=10.1677/joe.0.1570415
Metcalfe R.A., Findlay C., Robertson W.R., Weetman A.P., MacNeil S.
Differential effect of thyroid-stimulating hormone (TSH) on intracellular free calcium and cAMP in cells transfected with the human TSH receptor.
J. Endocrinol. 157:415-424(1998)

Cross-references
Encyclopedic resources Wikidata; Q94331701
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number8