Cellosaurus cell line 149RM (CVCL

Cellosaurus 149RM (CVCL_VL37)

[Text version]

Cell line name

149RM

Accession

CVCL_VL37

Resource Identification Initiative

To cite this cell line use: 149RM (RRID:CVCL_VL37)

Comments

Population: Chinese.
Doubling time: 26.39 hours (PubMed=29880898).
Omics: Genome sequenced.
Derived from site: Metastatic; Scrotum; UBERON=UBERON_0001300.

Sequence variations

Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Val (c.38G>T); ClinVar=VCV000180848; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro72Arg (c.215C>G); ClinVar=VCV000012351; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=29880898).

Disease

Squamous cell carcinoma of the penis (NCIt: C7729)
Squamous cell carcinoma of the penis (ORDO: Orphanet_398058)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_VF96 ! 149RCa

Sex of cell

Male

Age at sampling

33Y

Category

Cancer cell line

STR profile

Source(s): PubMed=29880898

Markers:

Amelogenin	X,Y
CSF1PO	10,11
D5S818	10
D7S820	12
D13S317	9,12
D16S539	12
TH01	6,9
TPOX	8
vWA	14,16

Publications

PubMed=29880898; DOI=10.1038/s41419-018-0736-1; PMCID=PMC5992159
Zhou Q.-H., Deng C.-Z., Li Z.-S., Chen J.-P., Yao K., Huang K.-B., Liu T.-Y., Liu Z.-W., Qin Z.-K., Zhou F.-J., Huang W., Han H., Liu R.-Y.
Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.
Cell Death Dis. 9:684.1-684.14(2018)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_VL37

Encyclopedic resources

Wikidata; Q93299258

Polymorphism and mutation databases

Cosmic; 2806957

Entry history

Entry creation

07-Sep-2018

Last entry update

19-Dec-2024

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