Cellosaurus cell line UKRV-Mel-32 (CVCL

Cellosaurus UKRV-Mel-32 (CVCL_VK54)

Cross-references
Cell line name	UKRV-Mel-32
Synonyms	UKRVMEL32
Accession	CVCL_VK54
Resource Identification Initiative	To cite this cell line use: UKRV-Mel-32 (RRID:CVCL_VK54)
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=26909863). Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (PubMed=26909863). Gene fusion; HGNC; HGNC:7413; MTAP + HGNC; HGNC:34341; CDKN2B-AS1; Name(s)=MTAP-ANRIL (PubMed=26909863). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=23348503; DOI=10.1126/science.1230062 Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R. TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013) PubMed=26909863; DOI=10.18632/oncotarget.7503; PMCID=PMC4941330 Xie H.-P., Rachakonda P.S., Heidenreich B., Nagore E., Sucker A., Hemminki K., Schadendorf D., Kumar R. Mapping of deletion breakpoints at the CDKN2A locus in melanoma: detection of MTAP-ANRIL fusion transcripts. Oncotarget 7:16490-16504(2016)
Encyclopedic resources	Wikidata; Q98133996
Polymorphism and mutation databases	Cosmic; 2686538
Entry history
Entry creation	07-Sep-2018
Last entry update	19-Dec-2024
Version number	6