Cellosaurus cell line K-EW1 (CVCL

Cross-references
Cell line name	K-EW1
Accession	CVCL_VK45
Resource Identification Initiative	To cite this cell line use: K-EW1 (RRID:CVCL_VK45)
Comments	Population: Japanese. Derived from site: In situ; Pelvic cavity; UBERON=UBERON_0008203.
Sequence variations	Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (PubMed=9738976).
Disease	Ewing sarcoma (NCIt: C4817) Ewing sarcoma (ORDO: Orphanet_319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	15Y
Category	Cancer cell line
Publications	PubMed=9738976; DOI=10.1111/j.1349-7006.1998.tb03274.x; PMCID=PMC5921883 Urano F., Umezawa A., Yabe H., Hong W., Yoshida K., Fujinaga K., Hata J.-i. Molecular analysis of Ewing's sarcoma: another fusion gene, EWS-E1AF, available for diagnosis. Jpn. J. Cancer Res. 89:703-711(1998) PubMed=12054564; DOI=10.1016/S0006-291X(02)00129-8 Yabe H., Fukuma M., Urano F., Yoshida K., Kato S., Toyama Y., Hata J.-i., Umezawa A. Lack of matrix metalloproteinase (MMP)-1 and -3 expression in Ewing sarcoma may be due to loss of accessibility of the MMP regulatory element to the specific fusion protein in vivo. Biochem. Biophys. Res. Commun. 293:61-71(2002)
Encyclopedic resources	Wikidata; Q94333838
Polymorphism and mutation databases	Cosmic; 1085903
Entry history
Entry creation	07-Sep-2018
Last entry update	19-Dec-2024
Version number	11