ID   VACO 8-2
AC   CVCL_VK10
SY   Vaco 8-2; VACO8-2; Vaco8-2
DR   cancercelllines; CVCL_VK10
DR   Cosmic; 2647360
DR   Wikidata; Q98134469
RX   PubMed=9927040;
CC   Microsatellite instability: Stable (MSS) (PubMed=9927040).
CC   Sequence variation: Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Asp522Asn (c.1564G>A); ClinVar=VCV000213936; Zygosity=Homozygous (PubMed=9927040).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leu (c.569C>T); ClinVar=VCV000418517; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Cecum; UBERON=UBERON_0001153.
DI   NCIt; C5543; Cecum adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_5411 ! VACO 8
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 19-12-24; Version: 9
//
RX   PubMed=9927040;
RA   Grady W.M., Myeroff L.L., Swinler S.E., Rajput A., Thiagalingam S.,
RA   Lutterbaugh J.D., Neumann A., Brattain M.G., Chang J., Kim S.-J.,
RA   Kinzler K.W., Vogelstein B., Willson J.K.V., Markowitz S.D.;
RT   "Mutational inactivation of transforming growth factor beta receptor
RT   type II in microsatellite stable colon cancers.";
RL   Cancer Res. 59:320-324(1999).
//