Cellosaurus cell line Co53 (CVCL

Cross-references
Cell line name	Co53
Accession	CVCL_VK05
Resource Identification Initiative	To cite this cell line use: Co53 (RRID:CVCL_VK05)
Sequence variations	Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (PubMed=12615714). Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (PubMed=12615714). Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Leu452Pro (c.1355T>C); ClinVar=VCV000930524; Zygosity=Heterozygous (PubMed=12615714).
Disease	Colon carcinoma (NCIt: C4910)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=12615714 Hempen P.M., Zhang L., Bansal R.K., Iacobuzio-Donahue C.A., Murphy K.M., Maitra A., Vogelstein B., Whitehead R.H., Markowitz S.D., Willson J.K.V., Yeo C.J., Hruban R.H., Kern S.E. Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res. 63:994-999(2003)
Cell line databases/resources	cancercelllines; CVCL_VK05
Encyclopedic resources	Wikidata; Q93456392
Polymorphism and mutation databases	Cosmic; 2667977
Entry history
Entry creation	07-Sep-2018
Last entry update	19-Dec-2024
Version number	8