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Cellosaurus SCCIC15 (CVCL_VJ51)

[Text version]
Cell line name SCCIC15
Accession CVCL_VJ51
Resource Identification Initiative To cite this cell line use: SCCIC15 (RRID:CVCL_VJ51)
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Ser106Pro (c.316T>C); Zygosity=Unspecified (PubMed=24662767).
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Gln1534Ter (c.4600C>T); Zygosity=Unspecified (PubMed=24662767).
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Gln1864Arg (c.5591A>G); ClinVar=VCV002100138; Zygosity=Unspecified (PubMed=24662767).
Disease Skin squamous cell carcinoma (NCIt: C4819)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=24662767; DOI=10.1038/jid.2014.154; PMCID=PMC4753672
South A.P., Purdie K.J., Watt S.A., Haldenby S., den Breems N.Y., Dimon M., Arron S.T., Kluk M.J., Aster J.C., McHugh A., Xue D.J., Dayal J.H.S., Robinson K.S., Rizvi S.M.H., Proby C.M., Harwood C.A., Leigh I.M.
NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis.
J. Invest. Dermatol. 134:2630-2638(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VJ51
Encyclopedic resources Wikidata; Q98129370
Polymorphism and mutation databases Cosmic; 2688664
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number8