Cellosaurus logo
expasy logo

Cellosaurus ORL-215 (CVCL_VJ48)

[Text version]
Cell line name ORL-215
Synonyms ORL-215T; 215T
Accession CVCL_VJ48
Resource Identification Initiative To cite this cell line use: ORL-215 (RRID:CVCL_VJ48)
Comments Population: Indian.
Omics: CRISPR phenotypic screen.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): PubMed=27050151

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133819,20
D3S135815,18
D5S81811
D7S82010,11
D8S117910,16
D13S3178,11
D16S53911
D18S5114,18
D19S43312,15.2
D21S1128,29
FGA22,23
TH016
TPOX11
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115
Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A., Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C.
Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.
PLoS ONE 8:E80229-E80229(2013)

PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689
Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P., Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G., Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A., Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C.
Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Oncotarget 7:27802-27818(2016)

PubMed=32990596; DOI=10.7554/eLife.57761; PMCID=PMC7591259
Chai A.W.-Y., Yee P.-S., Price S., Yee S.-M., Lee H.-M., Tiong V.K.H., Goncalves E., Behan F.M., Bateson J., Gilbert J.G.R., Tan A.-C., McDermott U., Garnett M.J., Cheong S.-C.
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
eLife 9:e57761.1-e57761.34(2020)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01995
CRISP screens repositories BioGRID_ORCS_Cell_line; 1281
Encyclopedic resources Wikidata; Q98128368
Polymorphism and mutation databases Cosmic; 2531644
Cosmic; 2559748
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number12