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Cellosaurus ORL-214 (CVCL_VJ47)

[Text version]
Cell line name ORL-214
Synonyms ORL-214T; 214T
Accession CVCL_VJ47
Resource Identification Initiative To cite this cell line use: ORL-214 (RRID:CVCL_VJ47)
Comments Population: Indian.
Omics: CRISPR phenotypic screen.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
Sequence variations
Disease Buccal mucosa squamous cell carcinoma (NCIt: C4040)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line
STR profile Source(s): PubMed=27050151

Markers:
AmelogeninX
CSF1PO10,12
D2S133819,21
D3S135815,16
D5S81811,13
D7S82010
D8S117913,16
D13S31710,12
D16S5399,11
D18S5113
D19S43312,13
D21S1130,33.2
FGA23,25
TH018,9
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115
Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A., Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C.
Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.
PLoS ONE 8:E80229-E80229(2013)

PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689
Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P., Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G., Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A., Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C.
Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Oncotarget 7:27802-27818(2016)

PubMed=32990596; DOI=10.7554/eLife.57761; PMCID=PMC7591259
Chai A.W.-Y., Yee P.-S., Price S., Yee S.-M., Lee H.-M., Tiong V.K.H., Goncalves E., Behan F.M., Bateson J., Gilbert J.G.R., Tan A.-C., McDermott U., Garnett M.J., Cheong S.-C.
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
eLife 9:e57761.1-e57761.34(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VJ47
Cell_Model_Passport; SIDM01996
CRISP screens repositories BioGRID_ORCS_Cell_line; 1280
Encyclopedic resources Wikidata; Q98128367
Polymorphism and mutation databases Cosmic; 2531653
Cosmic; 2559747
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number11