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Cellosaurus ORL-207 (CVCL_VJ46)

[Text version]
Cell line name ORL-207
Synonyms ORL-207T; 207T
Accession CVCL_VJ46
Resource Identification Initiative To cite this cell line use: ORL-207 (RRID:CVCL_VJ46)
Comments Population: Indian.
Omics: CRISPR phenotypic screen.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): PubMed=27050151

Markers:
AmelogeninX
CSF1PO9
D2S133818,23
D3S135815
D5S81812
D7S8208,13
D8S117912,16
D13S31712
D16S5399,13
D18S5112,18
D19S43313,15.2
D21S1130,31.2
FGA22
TH019.3
TPOX11,12
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115
Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A., Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C.
Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.
PLoS ONE 8:E80229-E80229(2013)

PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689
Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P., Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G., Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A., Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C.
Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Oncotarget 7:27802-27818(2016)

PubMed=32990596; DOI=10.7554/eLife.57761; PMCID=PMC7591259
Chai A.W.-Y., Yee P.-S., Price S., Yee S.-M., Lee H.-M., Tiong V.K.H., Goncalves E., Behan F.M., Bateson J., Gilbert J.G.R., Tan A.-C., McDermott U., Garnett M.J., Cheong S.-C.
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
eLife 9:e57761.1-e57761.34(2020)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01998
CRISP screens repositories BioGRID_ORCS_Cell_line; 1279
Encyclopedic resources Wikidata; Q98128366
Polymorphism and mutation databases Cosmic; 2531652
Cosmic; 2559746
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number12