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Cellosaurus ORL-204 (CVCL_VJ45)

[Text version]
Cell line name ORL-204
Synonyms ORL-204T; 204T
Accession CVCL_VJ45
Resource Identification Initiative To cite this cell line use: ORL-204 (RRID:CVCL_VJ45)
Comments Population: Indian.
Omics: CRISPR phenotypic screen.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
Sequence variations
Disease Buccal mucosa squamous cell carcinoma (NCIt: C4040)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): PubMed=27050151

Markers:
AmelogeninX,Y
CSF1PO12
D2S133820,21
D3S135815
D5S81812
D7S82012
D8S117915
D13S3178,9
D16S5399
D18S5116
D19S43311,13.2
D21S1132,34.2
FGA17
TH016,8
TPOX11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115
Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A., Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C.
Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.
PLoS ONE 8:E80229-E80229(2013)

PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689
Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P., Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G., Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A., Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C.
Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Oncotarget 7:27802-27818(2016)

PubMed=32990596; DOI=10.7554/eLife.57761; PMCID=PMC7591259
Chai A.W.-Y., Yee P.-S., Price S., Yee S.-M., Lee H.-M., Tiong V.K.H., Goncalves E., Behan F.M., Bateson J., Gilbert J.G.R., Tan A.-C., McDermott U., Garnett M.J., Cheong S.-C.
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
eLife 9:e57761.1-e57761.34(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VJ45
Cell_Model_Passport; SIDM02008
CRISP screens repositories BioGRID_ORCS_Cell_line; 1278
Encyclopedic resources Wikidata; Q98128365
Polymorphism and mutation databases Cosmic; 2531649
Cosmic; 2559745
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number12