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Cellosaurus ORL-166 (CVCL_VJ40)

[Text version]
Cell line name ORL-166
Synonyms ORL-166T; 166T
Accession CVCL_VJ40
Resource Identification Initiative To cite this cell line use: ORL-166 (RRID:CVCL_VJ40)
Comments Population: Malaysian.
Omics: CRISPR phenotypic screen.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): PubMed=27050151

Markers:
AmelogeninX
CSF1PO12
D2S133822,23
D3S135815,16
D5S81812
D7S82010,11
D8S117913,14
D13S31710,11
D16S53912
D18S5115
D19S43313,15
D21S1130.2,32.2
FGA21,24
TH019
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115
Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A., Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C.
Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.
PLoS ONE 8:E80229-E80229(2013)

PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689
Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P., Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G., Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A., Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C.
Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Oncotarget 7:27802-27818(2016)

PubMed=32990596; DOI=10.7554/eLife.57761; PMCID=PMC7591259
Chai A.W.-Y., Yee P.-S., Price S., Yee S.-M., Lee H.-M., Tiong V.K.H., Goncalves E., Behan F.M., Bateson J., Gilbert J.G.R., Tan A.-C., McDermott U., Garnett M.J., Cheong S.-C.
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
eLife 9:e57761.1-e57761.34(2020)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM02002
CRISP screens repositories BioGRID_ORCS_Cell_line; 1283
Encyclopedic resources Wikidata; Q98128359
Polymorphism and mutation databases Cosmic; 2531645
Cosmic; 2559740
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number12