Cellosaurus cell line Penl2 (CVCL

Cellosaurus Penl2 (CVCL_VF95)

[Text version]

Cell line name

Penl2

Accession

CVCL_VF95

Resource Identification Initiative

To cite this cell line use: Penl2 (RRID:CVCL_VF95)

Comments

Population: Chinese.
Doubling time: 28.38 hours (PubMed=29880898).
Omics: Genome sequenced.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Ser1613Gly (c.4837A>G); ClinVar=VCV000041827; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Arg922Gln (c.2765G>A); ClinVar=VCV000410514; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=29880898).

Disease

Squamous cell carcinoma of the penis (NCIt: C7729)
Squamous cell carcinoma of the penis (ORDO: Orphanet_398058)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

50Y

Category

Cancer cell line

STR profile

Source(s): PubMed=28344882; PubMed=29880898

Markers:

Amelogenin	X,Y
CSF1PO	11,13
D5S818	7,11
D7S820	11,13
D13S317	8,12
D16S539	9,11
TH01	6,9
TPOX	9,11
vWA	18

Publications

PubMed=28344882; DOI=10.1080/2162402X.2016.1269047; PMCID=PMC5353932
Deng C.-Z., Li Z.-S., Guo S.-J., Chen P., Chen X.-F., Zhou Q.-H., Chen J.-P., Yu X.-S., Wu X.-L., Ma W.-J., Xie Q.-K., Ye Y.-L., Li Y.-H., Qin Z.-K., Liu Z.-W., Liu R.-Y., Zhang Z.-F., Yao K., Han H., Zhou F.-J.
Tumor PD-L1 expression is correlated with increased TILs and poor prognosis in penile squamous cell carcinoma.
OncoImmunology 6:e1269047.1-e1269047.8(2017)

PubMed=29880898; DOI=10.1038/s41419-018-0736-1; PMCID=PMC5992159
Zhou Q.-H., Deng C.-Z., Li Z.-S., Chen J.-P., Yao K., Huang K.-B., Liu T.-Y., Liu Z.-W., Qin Z.-K., Zhou F.-J., Huang W., Han H., Liu R.-Y.
Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.
Cell Death Dis. 9:684.1-684.14(2018)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_VF95

Encyclopedic resources

Wikidata; Q54946919

Polymorphism and mutation databases

Cosmic; 2806955

Entry history

Entry creation

14-May-2018

Last entry update

19-Dec-2024

Version number