Cellosaurus cell line FUS1 (CVCL

Cross-references
Cell line name	FUS1
Accession	CVCL_VF85
Resource Identification Initiative	To cite this cell line use: FUS1 (RRID:CVCL_VF85)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:4010; FUS; Simple; p.Arg521Cys (c.1561C>T); ClinVar=VCV000016224; Zygosity=Heterozygous (PubMed=28082870).
Disease	Amyotrophic lateral sclerosis 6, with or without frontotemporal dementia (NCIt: C168750) Amyotrophic lateral sclerosis (ORDO: Orphanet_803)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	58Y
Category	Induced pluripotent stem cell
Publications	PubMed=28082870; DOI=10.3389/fncel.2016.00290; PMCID=PMC5183648 Higelin J., Demestre M., Putz S., Delling J.P., Jacob C., Lutz A.-K., Bausinger J., Huber A.-K., Klingenstein M., Barbi G., Speit G., Huebers A., Weishaupt J.H., Hermann A., Liebau S., Ludolph A.C., Boeckers T.M. FUS mislocalization and vulnerability to DNA damage in ALS patients derived hiPSCs and aging motoneurons. Front. Cell. Neurosci. 10:290.1-290.21(2016)
Cell line databases/resources	SKIP; SKIP001729
Encyclopedic resources	Wikidata; Q54835271
Entry history
Entry creation	14-May-2018
Last entry update	19-Dec-2024
Version number	10