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Cellosaurus BJAB GFP-MS4A4A (CVCL_VD93)

[Text version]
Cell line name BJAB GFP-MS4A4A
Synonyms BJAB MS4A4A-GFP
Accession CVCL_VD93
Resource Identification Initiative To cite this cell line use: BJAB GFP-MS4A4A (RRID:CVCL_VD93)
Comments Population: African; Kenyan.
Characteristics: Expresses GFP fused to the N-terminus of MS4A4A/CD20L1.
Virology: EBV-negative.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:13371; MS4A4A.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=23874341; DOI=10.3389/fimmu.2013.00195; PMCID=PMC3711070
Zuccolo J., Deng L.-L., Unruh T.L., Sanyal R., Bau J.A., Storek J., Demetrick D.J., Luider J.M., Auer-Grzesiak I.A., Mansoor A., Deans J.P.
Expression of MS4A and TMEM176 genes in human B lymphocytes.
Front. Immunol. 4:195.1-195.7(2013)

PubMed=28303902; DOI=10.1038/icb.2017.18
Sanyal R., Polyak M.J., Zuccolo J., Puri M., Deng L.-L., Roberts L., Zuba A., Storek J., Luider J.M., Sundberg E.M., Mansoor A., Baigorri E., Chu M.P., Belch A.R., Pilarski L.M., Deans J.P.
MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells.
Immunol. Cell Biol. 95:611-619(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VD93
Encyclopedic resources Wikidata; Q54796979
Entry history
Entry creation14-May-2018
Last entry update19-Dec-2024
Version number12