Cellosaurus cell line INCABRi002-A (CVCL

Cross-references
Cell line name	INCABRi002-A
Synonyms	PMF3.17
Accession	CVCL_VD83
Resource Identification Initiative	To cite this cell line use: INCABRi002-A (RRID:CVCL_VD83)
Comments	From: Instituto Nacional de Cancer (INCA); Rio de Janeiro; Brazil. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:1455; CALR; Simple; p.Lys385Asnfs*47 (c.1154_1155insTTGTC) (CALRins5); ClinVar=VCV001028735; Zygosity=Heterozygous (PubMed=30343103). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp146Ter (c.437G>A); ClinVar=VCV000634785; Zygosity=Homozygous (PubMed=30343103).
Disease	Primary myelofibrosis (NCIt: C2862) Primary myelofibrosis (ORDO: Orphanet_824)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	65Y
Category	Induced pluripotent stem cell
Publications	PubMed=30343103; DOI=10.1016/j.scr.2018.09.012 Gomez Limia C.E., Devalle S., Reis M., Sochacki J., Madeiro da Costa R., D'Andrea M., Padilha T., Zalcberg I.R., Solza C., Daumas A., Rehen S.K., Bonamino M.H., Monte-Mor B. Characterization of a human induced pluripotent stem (iPS) cell line (INCABRi002-A) derived from a primary myelofibrosis patient harboring the 5-bp insertion in CALR and the p.W146X mutation in TP53. Stem Cell Res. 33:130-134(2018)
Cell line databases/resources	hPSCreg; INCABRi002-A
Encyclopedic resources	Wikidata; Q54897707
Entry history
Entry creation	14-May-2018
Last entry update	19-Dec-2024
Version number	10