ID   US/VOT-E36
AC   CVCL_VC36
SY   VOT-E36; University of Sheffield/Ventral OTocyst-Epithelial 36
DR   CancerTools; 153625
DR   Wikidata; Q54991846
DR   Ximbio; 153625
RX   PubMed=15499550;
RX   PubMed=17331193;
WW   https://licensing.sheffield.ac.uk/fileserver/5
CC   Characteristics: Suitable for studies on inner ear development, gene expression and function of inner ear-specific genes, in vitro screening for gene activation and promoter analysis, ototoxicity and in vitro analysis of inherited deafness mutations and of ion channels, receptors and signalling pathways in vitro.
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Embryonic ear, inner ear, otocyst; UBERON=UBERON_0003051.
CC   Cell type: Epithelial cell; CL=CL_0000066.
CC   Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   10-11FD
CA   Conditionally immortalized cell line
DT   Created: 14-05-18; Last updated: 10-09-24; Version: 10
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RX   PubMed=15499550; DOI=10.1002/dvdy.20187;
RA   Lawoko-Kerali G., Milo M., Davies D., Halsall A., Helyer R.J.,
RA   Johnson C.M., Rivolta M.N., Tones M.A., Holley M.C.;
RT   "Ventral otic cell lines as developmental models of auditory
RT   epithelial and neural precursors.";
RL   Dev. Dyn. 231:801-814(2004).
//
RX   PubMed=17331193; DOI=10.1111/j.1460-9568.2007.05338.x;
RA   Helyer R.J., Cacciabue-Rivolta D.I., Davies D., Rivolta M.N., Kros C.J.,
RA   Holley M.C.;
RT   "A model for mammalian cochlear hair cell differentiation in vitro:
RT   effects of retinoic acid on cytoskeletal proteins and potassium
RT   conductances.";
RL   Eur. J. Neurosci. 25:957-973(2007).
//