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Cellosaurus HCC630 (CVCL_V729)

[Text version]
Cell line name HCC630
Synonyms HCC0630; Hamon Cancer Center 630
Accession CVCL_V729
Resource Identification Initiative To cite this cell line use: HCC630 (RRID:CVCL_V729)
Comments Problematic cell line: Possibly misidentified. Presence of a Y chromosome in cell line that was thought to be of female origin (STR profile).
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
HLA typing Source: PubMed=26589293
Class I
HLA-AA*11:01,24:02
HLA-BB*18:01,37:01
HLA-CC*07:04,07:04
Disease Ovarian carcinoma (NCIt: C4908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO11
D3S135813,16
D5S81812
D7S8208,12
D8S117913,16
D13S31711,12,13
D16S53911,12
D18S5115,16
D21S1130,33.2
FGA20.2,21
Penta D15
Penta E7
TH017,9
TPOX8,9
vWA15,16,17,18

Run an STR similarity search on this cell line
Web pages http://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
Publications

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

Cross-references
Biological sample resources BioSample; SAMN03472978
Chemistry resources PharmacoDB; HCC630_508_2019
Encyclopedic resources Wikidata; Q54881770
Experimental variables resources EFO; EFO_0006421
Gene expression databases ArrayExpress; E-MTAB-2706
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number15