Cellosaurus logo
expasy logo

Cellosaurus L10BIOBR-MAPKK (CVCL_V173)

[Text version]
Cell line name L10BIOBR-MAPKK
Accession CVCL_V173
Resource Identification Initiative To cite this cell line use: L10BIOBR-MAPKK (RRID:CVCL_V173)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:1346866; Map2k1 (Note=Constitutively activated form).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Melanocyte of skin; CL=CL_1000458.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: B10.BR.
Hierarchy Parent: CVCL_V171 (L10BIOBR)
Category Transformed cell line
Publications

PubMed=12514183; DOI=10.1074/jbc.M212929200
Govindarajan B., Bai X.-H., Cohen C., Zhong H., Kilroy S., Louis G., Moses M.A., Arbiser J.L.
Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling.
J. Biol. Chem. 278:9790-9795(2003)

Cross-references
Cell line collections (Providers) ATCC; CRL-2771
Encyclopedic resources Wikidata; Q54900943
Entry history
Entry creation16-Apr-2014
Last entry update10-Sep-2024
Version number8