Cellosaurus AND-1 MLLAF4 FLT3 D835 (CVCL_V163)
| Cell line name | AND-1 MLLAF4 FLT3 D835 |
|---|---|
| Synonyms | AND1-MLLAF4 FLT3 D835; AND1-MLLAF4/FLT3-TKD |
| Accession | CVCL_V163 |
| Resource Identification Initiative | To cite this cell line use: AND-1 MLLAF4 FLT3 D835 (RRID:CVCL_V163) |
| Comments | Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection. From: Centre for Genomics and Oncological Research (GENYO); Granada; Spain. Characteristics: Transduced with both a pRRL-EF1a-MLLAF4-PGKp-Neo and a pRRL-EF1a-FLT3 D835-PGKp-GFP constructs. Karyotypic information: 46,XY,+i(7)p(11),-7 (BNLC). Genetic integration: Method=Transduction; Gene=HGNC; 7135; AFF1 (Note=KMT2-AFF1/MLL-AF4 fusion). Genetic integration: Method=Transduction; Gene=HGNC; 7132; KMT2A (Note=KMT2-AFF1/MLL-AF4 fusion). Genetic integration: Method=Transduction; Gene=HGNC; 3765; FLT3 (Note=With p.Asp835Xaa). Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_B526 (AND-1) |
| Sex of cell | Male |
| Age at sampling | Blastocyst stage |
| Category | Embryonic stem cell |
| Web pages | https://www.isciii.es/QueHacemos/Servicios/BIOBANCOS/BNLC/Lists/Lneas%20embrionarias/Attachments/36/Caracteristicas%20-%20Dossier-AND1-FLT3-D835.pdf |
| Publications | PubMed=23479570; DOI=10.1182/blood-2012-11-470146 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54749922 |
| Entry history | |
| Entry creation | 16-Apr-2014 |
| Last entry update | 10-Sep-2024 |
| Version number | 11 |